Monday, November 09, 2009

An Update

We're somewhere around the middle of the pregnancy.  The spotting for the most part went away.  She still spots occasionally which makes us uneasy.  Also, BJ reports that it is harder to give herself the shots than she recalled it being with our other baby.  The needle is harder to push into the flesh and it often burns.  You can feel some knots under the skin from where she has given herself shots.  Her belly is bruised badly from the blood thinners.  But the doctor's continue to report that everything appears to be going well.  

When we did the last ultrasound, we were unable to tell the gender.  But they said that the heart rate was fast and in the range for a girl.  At the last doctor's visit, they said that the heart rate was in the range for a boy.  On November 30th, we'll lay the gender question to rest.  On that day, we'll be getting a 3D ultrasound.  We're so excited! 

BJ's actually lost some weight.  When not pregnant, BJ suffered from severe migraine headaches the source of which we were never able to determine.  Once again, during pregnancy the headaches have almost all gone away.  She has them occasionally but not nearly as badly as before.  I'm still convinced that they are somehow related to the MTHFR mutation.  My theory is that there is something in the prenatal vitamins or folic acid itself that is preventing the headaches.  I wonder how many others with the MTHFR mutation have experienced migraines and whether or not they've gone away when taking vitamins.


Lori said...

So happy to hear the pregnancy is progressing well! :)

Since I was 15 or 16 years old up until a couple of months ago I suffered from at least 2 migraines a month.

Upon discovering I have mthfr with one copy each of both mutations, my Dr. prescribed 4 mg of folate per day and told me to take a baby aspirin everyday...I will be on both for the rest of my life.

Well, the changes I've gone through have been dramatically positive! It's been 2+ months since I commenced taking the aspirin and folate and I haven't had a headache, migraine, or hint of a migraine wanting to start. I can also eat chocolate again, which I could NEVER do before without a guaranteed migraine.

Anonymous said...

I'm homozygous for MTHFR, had only a handful of migraines before I became pregnant, but experienced about 1-2 a week for a few weeks around the middle of my pregnancy. I didn't know I had MTHFR then and I have no idea if that had anything to do with it, but it was horrible! Still, it's strange that folic acid seems to be helping some people. I wonder what was going on in my case.

ZerlinaZ said...

My doctor treats MTHFR with a percription of methyl folate (deplin) and methyl B12 along with a whole host of other asprin. This regimine is for the rest of my life. He said this should be the end of my migraines. He showed me a medical journal article linking MTHFR to migraines, IBS, and other conditions.

Anonymous said...

I'd be interested to see the medical journal article as to what other conditions MTHFR links to; I also have homozygous MTHFR and have a severe GERD all the time except when I am pregnant. While I'm sure the migranes are connected to the condition and relieved w/ treatment,it appears my GERD is much the same way. I am also currently pregnant and treated w/ a B12, folic acid vitamin therapy, along with a baby aspirin, that has led to 2, now 3, healthy children. Good luck to you and your wife!

Anonymous said...

Excerpt from an Aug 2009 Life Extension article:

Active Folate: Relief For Migraine Sufferers
Migraine is a debilitating inflammatory blood vessel disease that may be triggered by damage inflicted by elevated blood levels of homocysteine to the endothelium of blood vessels in the brain.31

A recent study showed that treatment with B-complex vitamins, including 5-MTHF, might provide relief for migraine sufferers including those with the MTHFR C677T genotype, which typically limits the clinical effectiveness of supplemental folic acid.7

Headache frequency and pain severity were also reduced. The treatment effect proved successful in reducing homocysteine levels and migraine disability in study participants with the MTHFR C677T genotype.7 Researchers have long suspected that migraine headaches have a genetic component, because migraine sufferers often have family members who also have the condition. Studies suggest that MTHFR polymorphisms may account for the genetic predisposition to migraine in some individuals.32

Anonymous said...

MTHFR can (can should) be treated with prescription METANX - it's methylated folate, B12 and bioactive form basically, so no metabolite by-products that can become toxic with OTC folic acid, B12 nad B6.